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A whole-animal platform to advance a clinical kinase inhibitor into new disease space.
Sonoshita, Masahiro; Scopton, Alex P; Ung, Peter M U; Murray, Matthew A; Silber, Lisa; Maldonado, Andres Y; Real, Alexander; Schlessinger, Avner; Cagan, Ross L; Dar, Arvin C.
Afiliação
  • Sonoshita M; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Scopton AP; Department of Systems Neuropharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Ung PMU; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Murray MA; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Silber L; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Maldonado AY; Department of Biomedical Sciences, Florida State University, Tallahassee, Florida, USA.
  • Real A; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Schlessinger A; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Cagan RL; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Dar AC; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Nat Chem Biol ; 14(3): 291-298, 2018 03.
Article em En | MEDLINE | ID: mdl-29355849
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Carcinoma / Carcinoma Neuroendócrino / Inibidores de Proteínas Quinases / Drosophila Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Carcinoma / Carcinoma Neuroendócrino / Inibidores de Proteínas Quinases / Drosophila Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos