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Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.
Schrader, A; Crispatzu, G; Oberbeck, S; Mayer, P; Pützer, S; von Jan, J; Vasyutina, E; Warner, K; Weit, N; Pflug, N; Braun, T; Andersson, E I; Yadav, B; Riabinska, A; Maurer, B; Ventura Ferreira, M S; Beier, F; Altmüller, J; Lanasa, M; Herling, C D; Haferlach, T; Stilgenbauer, S; Hopfinger, G; Peifer, M; Brümmendorf, T H; Nürnberg, P; Elenitoba-Johnson, K S J; Zha, S; Hallek, M; Moriggl, R; Reinhardt, H C; Stern, M-H; Mustjoki, S; Newrzela, S; Frommolt, P; Herling, M.
Afiliação
  • Schrader A; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Crispatzu G; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Oberbeck S; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Mayer P; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Pützer S; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • von Jan J; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Vasyutina E; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Warner K; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Weit N; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Pflug N; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Braun T; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Andersson EI; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Yadav B; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Riabinska A; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Maurer B; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Ventura Ferreira MS; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Beier F; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Altmüller J; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Lanasa M; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Herling CD; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Haferlach T; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Stilgenbauer S; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Hopfinger G; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Peifer M; Senckenberg Institute of Pathology, Goethe-University, Frankfurt/M., 60590, Germany.
  • Brümmendorf TH; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Nürnberg P; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Elenitoba-Johnson KSJ; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Zha S; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Hallek M; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Moriggl R; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Reinhardt HC; CMMC, Center for Molecular Medicine University of Cologne (UoC), Köln, 50937, Germany.
  • Stern MH; Hematology Research Unit Helsinki, Department of Medicine and Clinical Chemistry, University of Helsinki and Helsinki University Central Hospital (HUCH), Helsinki, 00260, Finland.
  • Mustjoki S; Hematology Research Unit Helsinki, Department of Medicine and Clinical Chemistry, University of Helsinki and Helsinki University Central Hospital (HUCH), Helsinki, 00260, Finland.
  • Newrzela S; Department of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne (UoC), Köln, 50937, Germany.
  • Frommolt P; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Köln, 50937, Germany.
  • Herling M; Institute of Animal Breeding and Genetics, University of Veterinary Medicine; Ludwig Boltzmann Institute for Cancer Research, Medical University of Vienna, Vienna, 1210, Austria.
Nat Commun ; 9(1): 697, 2018 02 15.
Article em En | MEDLINE | ID: mdl-29449575
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Dano ao DNA / Leucemia Prolinfocítica de Células T / Proteínas Proto-Oncogênicas / Epigênese Genética / Proteínas Mutadas de Ataxia Telangiectasia Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Dano ao DNA / Leucemia Prolinfocítica de Células T / Proteínas Proto-Oncogênicas / Epigênese Genética / Proteínas Mutadas de Ataxia Telangiectasia Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha