Your browser doesn't support javascript.
loading
Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy.
Zha, Chuantao; Deng, Wenjia; Fu, Yan; Tang, Shuai; Lan, Xiaojing; Ye, Yan; Su, Yi; Jiang, Lei; Chen, Yi; Huang, Ying; Ding, Jian; Geng, Meiyu; Huang, Min; Wan, Huixin.
Afiliação
  • Zha C; Shanghai HaiHe Pharmaceutical, Co. Ltd, No. 421 Newton Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Deng W; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Fu Y; Shanghai HaiHe Pharmaceutical, Co. Ltd, No. 421 Newton Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Tang S; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Lan X; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Ye Y; Shanghai HaiHe Pharmaceutical, Co. Ltd, No. 421 Newton Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Su Y; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Jiang L; Shanghai HaiHe Pharmaceutical, Co. Ltd, No. 421 Newton Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Chen Y; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Huang Y; Shanghai HaiHe Pharmaceutical, Co. Ltd, No. 421 Newton Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Ding J; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Geng M; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Huang M; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China. Electronic address: mhuang@simm.ac.cn.
  • Wan H; Shanghai HaiHe Pharmaceutical, Co. Ltd, No. 421 Newton Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China. Electronic address: hxwan1978@hotmail.com.
Eur J Med Chem ; 148: 140-153, 2018 Mar 25.
Article em En | MEDLINE | ID: mdl-29459274
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tetra-Hidronaftalenos / Quinases Ciclina-Dependentes / Inibidores de Proteínas Quinases Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tetra-Hidronaftalenos / Quinases Ciclina-Dependentes / Inibidores de Proteínas Quinases Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China