Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects.

Nugent, Allison C; Ballard, Elizabeth D; Gould, Todd D; Park, Lawrence T; Moaddel, Ruin; Brutsche, Nancy E; Zarate, Carlos A

Nugent, Allison C; Ballard, Elizabeth D; Gould, Todd D; Park, Lawrence T; Moaddel, Ruin; Brutsche, Nancy E; Zarate, Carlos A.

Afiliação

Nugent AC; Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. nugenta@mail.nih.gov.
Ballard ED; Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Gould TD; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Park LT; Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Moaddel R; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, USA.
Brutsche NE; Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Zarate CA; Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.

Mol Psychiatry ; 24(7): 1040-1052, 2019 07.

Article em En | MEDLINE | ID: mdl-29487402

Assuntos

Depressão/tratamento farmacológico; Ketamina/metabolismo; Ketamina/farmacologia; Adulto; Antidepressivos/farmacologia; Estudos de Casos e Controles; Estudos Cross-Over; Transtorno Depressivo Maior/tratamento farmacológico; Transtorno Depressivo Resistente a Tratamento/tratamento farmacológico; Método Duplo-Cego; Fenômenos Eletrofisiológicos/fisiologia; Feminino; Humanos; Magnetoencefalografia/métodos; Masculino; Pessoa de Meia-Idade

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Depressão / Ketamina Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Psychiatry Assunto da revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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