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Pulmonary vascular endothelium: the orchestra conductor in respiratory diseases: Highlights from basic research to therapy.
Huertas, Alice; Guignabert, Christophe; Barberà, Joan A; Bärtsch, Peter; Bhattacharya, Jahar; Bhattacharya, Sunita; Bonsignore, Maria R; Dewachter, Laurence; Dinh-Xuan, Anh Tuan; Dorfmüller, Peter; Gladwin, Mark T; Humbert, Marc; Kotsimbos, Tom; Vassilakopoulos, Theodoros; Sanchez, Olivier; Savale, Laurent; Testa, Ugo; Wilkins, Martin R.
Afiliação
  • Huertas A; INSERM UMR_S 999, Hôpital Marie Lannelongue, Université Paris-Sud/Université Paris-Saclay, AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Plessis-Robinson and Le Kremlin-Bicêtre, France.
  • Guignabert C; A. Huertas and C. Guignabert have contributed equally. They are both first authors and are co-chairs of the European Respiratory Society (ERS) Research Seminar Faculty.
  • Barberà JA; INSERM UMR_S 999, Hôpital Marie Lannelongue, Université Paris-Sud/Université Paris-Saclay, AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Plessis-Robinson and Le Kremlin-Bicêtre, France.
  • Bärtsch P; A. Huertas and C. Guignabert have contributed equally. They are both first authors and are co-chairs of the European Respiratory Society (ERS) Research Seminar Faculty.
  • Bhattacharya J; Dept of Pulmonary Medicine, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
  • Bhattacharya S; Centro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES), Madrid, Spain.
  • Bonsignore MR; Dept of Internal Medicine, University Clinic Heidelberg, Heidelberg, Germany.
  • Dewachter L; Lung Biology Lab, Dept of Medicine, Columbia University Medical Center, New York, NY, USA.
  • Dinh-Xuan AT; Lung Biology Lab, Dept of Medicine, Columbia University Medical Center, New York, NY, USA.
  • Dorfmüller P; Institute of Biomedicine and Molecular Immunology (IBIM), National Research Council (CNR), Biomedical Dept of Internal and Specialistic Medicine (DiBiMIS), University of Palermo, Palermo, Italy.
  • Gladwin MT; Laboratory of Physiology and Pharmacology, Université Libre de Bruxelles (Campus Erasme), Brussels, Belgium.
  • Humbert M; Respiratory Physiology Unit, Cardiothoracic Dept, Cochin Hospital, Paris Descartes University, Paris, France.
  • Kotsimbos T; INSERM UMR_S 999, Hôpital Marie Lannelongue, Université Paris-Sud/Université Paris-Saclay, AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Plessis-Robinson and Le Kremlin-Bicêtre, France.
  • Vassilakopoulos T; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, Division of Pulmonary, Allergy and Critical Care Medicine, Dept of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Sanchez O; INSERM UMR_S 999, Hôpital Marie Lannelongue, Université Paris-Sud/Université Paris-Saclay, AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Plessis-Robinson and Le Kremlin-Bicêtre, France.
  • Savale L; Alfred Health, Monash University, Melbourne, Australia.
  • Testa U; Pulmonary and Critical Care Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Wilkins MR; Dept of Pulmonology, AP-HP, Georges Pompidou European Hospital, Sorbonne Paris City, Medical School, Paris Descartes University, Paris, France.
Eur Respir J ; 51(4)2018 04.
Article em En | MEDLINE | ID: mdl-29545281
ABSTRACT
The European Respiratory Society (ERS) Research Seminar entitled "Pulmonary vascular endothelium orchestra conductor in respiratory diseases - highlights from basic research to therapy" brought together international experts in dysfunctional pulmonary endothelium, from basic science to translational medicine, to discuss several important aspects in acute and chronic lung diseases. This review will briefly sum up the different topics of discussion from this meeting which was held in Paris, France on October 27-28, 2016. It is important to consider that this paper does not address all aspects of endothelial dysfunction but focuses on specific themes such as 1) the complex role of the pulmonary endothelium in orchestrating the host response in both health and disease (acute lung injury, chronic obstructive pulmonary disease, high-altitude pulmonary oedema and pulmonary hypertension); and 2) the potential value of dysfunctional pulmonary endothelium as a target for innovative therapies.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doenças Respiratórias / Endotélio Vascular Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Eur Respir J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doenças Respiratórias / Endotélio Vascular Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Eur Respir J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França