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Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway.
Fan, Jianjia; Zhao, Rui Qi; Parro, Cameron; Zhao, Wenchen; Chou, Hsien-Ya; Robert, Jerome; Deeb, Tarek Z; Raynoschek, Carina; Barichievy, Samantha; Engkvist, Ola; Maresca, Marcello; Hicks, Ryan; Meuller, Johan; Moss, Stephen J; Brandon, Nicholas J; Wood, Michael W; Kulic, Iva; Wellington, Cheryl L.
Afiliação
  • Fan J; Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Zhao RQ; Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Parro C; Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Zhao W; Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Chou HY; Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Robert J; Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Deeb TZ; Tufts-AstraZeneca Laboratory for Basic and Translational Neuroscience, Boston, MA.
  • Raynoschek C; Discovery Sciences, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Barichievy S; Discovery Sciences, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Engkvist O; Discovery Sciences, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Maresca M; Discovery Sciences, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Hicks R; Discovery Sciences, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Meuller J; Discovery Sciences, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Moss SJ; Tufts-AstraZeneca Laboratory for Basic and Translational Neuroscience, Boston, MA.
  • Brandon NJ; Department of Neuroscience, Tufts University School of Medicine, Boston, MA and Department of Neuroscience, Physiology, and Pharmacology, University College London, London, United Kingdom.
  • Wood MW; Neuroscience, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Boston, MA.
  • Kulic I; Neuroscience, Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Boston, MA.
  • Wellington CL; Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
J Lipid Res ; 59(5): 830-842, 2018 05.
Article em En | MEDLINE | ID: mdl-29563219
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Apolipoproteínas E / Bibliotecas de Moléculas Pequenas / Receptores Purinérgicos P2X7 / Antagonistas do Receptor Purinérgico P2X / Transportador 1 de Cassete de Ligação de ATP Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Lipid Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Apolipoproteínas E / Bibliotecas de Moléculas Pequenas / Receptores Purinérgicos P2X7 / Antagonistas do Receptor Purinérgico P2X / Transportador 1 de Cassete de Ligação de ATP Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Lipid Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá