Impact of high intensity interval exercise on executive function and brain derived neurotrophic factor in healthy college aged males.
Physiol Behav
; 191: 116-122, 2018 07 01.
Article
em En
| MEDLINE
| ID: mdl-29673858
ABSTRACT
BACKGROUND:
Prefrontal cortex (PFC)-dependent executive function is enhanced immediately following high intensity interval exercise (HIIE). Brain-derived neurotrophic factor (BDNF) is considered a biomarker associated with enhanced execute functioning capacity at rest and in response to exercise. However, the mechanisms responsible for the acute exercise-induced BDNF response in plasma and serum differ, and it is likely that the utilization of BDNF in plasma and/or serum as a biomarker of improved executive function following HIIE may be limited. Therefore, this study examined the impact of HIIE on the plasma and serum BDNF response to understand the efficaciousness of BDNF as a peripheral biomarker associated with improvements in PFC-dependent executive function. Thirteen healthy males (age 23.62⯱â¯1.06â¯years) participated in a randomized, counterbalanced study, performing the Wisconsin Card Sorting Task (WCST) immediately following a 5-minute seated rest (control) and participation in a HIIE protocol administered two weeks apart. HIIE consisted of ten maximal bouts of all out pedaling on a cycle ergometer for 20â¯s (separated by 10â¯s of active recovery) against 5.5% of the subject's body weight. Whole blood was collected for the assessment of BDNF in both plasma and serum. Compared to the control session, HIIE elicited significant improvements in WCST performance, yet improvements in PFC-dependent executive function were independent of BDNF concentrations in plasma and serum. Results from this investigation demonstrate that a single session of low-volume, supramaximal HIIE significantly increases PFC-dependent executive function, thereby providing additional evidence to support the powerful benefits on HIIE on cognitive functioning.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Exercício Físico
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Córtex Pré-Frontal
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Fator Neurotrófico Derivado do Encéfalo
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Função Executiva
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Treinamento Intervalado de Alta Intensidade
Tipo de estudo:
Clinical_trials
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Physiol Behav
Ano de publicação:
2018
Tipo de documento:
Article