Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults.

Parsons, Martin E M; Szklanna, Paulina B; Guerrero, Jose A; Wynne, Kieran; Dervin, Feidhlim; O'Connell, Karen; Allen, Seamus; Egan, Karl; Bennett, Cavan; McGuigan, Christopher; Gheveart, Cedric; Ní Áinle, Fionnuala; Maguire, Patricia B

Parsons, Martin E M; Szklanna, Paulina B; Guerrero, Jose A; Wynne, Kieran; Dervin, Feidhlim; O'Connell, Karen; Allen, Seamus; Egan, Karl; Bennett, Cavan; McGuigan, Christopher; Gheveart, Cedric; Ní Áinle, Fionnuala; Maguire, Patricia B.

Afiliação

Parsons MEM; SPHERE research group, Conway Institute, University College Dublin, Dublin 4, Ireland.
Szklanna PB; Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Guerrero JA; School of Biomolecular and Biomedical Science, University College Dublin, Dublin 4, Ireland.
Wynne K; SPHERE research group, Conway Institute, University College Dublin, Dublin 4, Ireland.
Dervin F; Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
O'Connell K; School of Biomolecular and Biomedical Science, University College Dublin, Dublin 4, Ireland.
Allen S; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Camebridge, United Kingdom.
Egan K; National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom.
Bennett C; Proteomics Core, Conway Institute, University College Dublin, Dublin 4, Ireland.
McGuigan C; School of Biomolecular and Biomedical Science, University College Dublin, Dublin 4, Ireland.
Gheveart C; Department of Neurology, St Vincent's University Hospital, Dublin 4, Ireland.
Ní Áinle F; School of Medicine, University College Dublin, Dublin 4, Ireland.
Maguire PB; SPHERE research group, Conway Institute, University College Dublin, Dublin 4, Ireland.

Proteomics ; 18(15): e1800219, 2018 08.

Article em En | MEDLINE | ID: mdl-29932309

Assuntos

Plaquetas/metabolismo; Proteínas Sanguíneas/metabolismo; Biologia Computacional/métodos; Proteoma/análise; Vesículas Secretórias/metabolismo; Espectrometria de Massas em Tandem/métodos; Adulto; Animais; Proteínas Sanguíneas/fisiologia; Modelos Animais de Doenças; Feminino; Síndrome da Plaqueta Cinza/fisiopatologia; Voluntários Saudáveis; Humanos; Masculino; Camundongos; Camundongos Knockout; Pessoa de Meia-Idade; Nanopartículas/química; Adulto Jovem

Palavras-chave

extracellular vesicles; label-free quantification; platelet releasate; platelets; tandem MS

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Plaquetas / Proteínas Sanguíneas / Biologia Computacional / Proteoma / Vesículas Secretórias / Espectrometria de Massas em Tandem Tipo de estudo: Qualitative_research Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Proteomics Assunto da revista: BIOQUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Irlanda

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