Isolation of human monoclonal antibodies that bind to two different antigens and are encoded by germline V<sub>H</sub> and V<sub>L</sub> genes.

Sumitomo-Kondo, M; Ukai, Y; Iba, Y; Ohshima, N; Miura, K; Takasaki, A; Kurosawa, Y; Kurosawa, G

Isolation of human monoclonal antibodies that bind to two different antigens and are encoded by germline V_H and V_L genes.

Sumitomo-Kondo, M; Ukai, Y; Iba, Y; Ohshima, N; Miura, K; Takasaki, A; Kurosawa, Y; Kurosawa, G.

Afiliação

Sumitomo-Kondo M; Center for Research Promotion and Support, Fujita Health University, Toyoake, Aichi, Japan; Perseus Proteomics Inc., Tokyo, Japan.
Ukai Y; Center for Research Promotion and Support, Fujita Health University, Toyoake, Aichi, Japan; Perseus Proteomics Inc., Tokyo, Japan.
Iba Y; Center for Research Promotion and Support, Fujita Health University, Toyoake, Aichi, Japan.
Ohshima N; Center for Research Promotion and Support, Fujita Health University, Toyoake, Aichi, Japan.
Miura K; School of Health Sciences Fujita Health University, Toyoake, Japan.
Takasaki A; Department of Medical Technology School of Health Sciences, Gifu University of Medical Science, Gifu, Japan.
Kurosawa Y; Center for Research Promotion and Support, Fujita Health University, Toyoake, Aichi, Japan.
Kurosawa G; Center for Research Promotion and Support, Fujita Health University, Toyoake, Aichi, Japan. Electronic address: gene@fujita-hu.ac.jp.

Biochem Biophys Res Commun ; 503(2): 1141-1147, 2018 09 05.

Article em En | MEDLINE | ID: mdl-29944883

Assuntos

Actinina/imunologia; Anticorpos Monoclonais/imunologia; Molécula 1 de Adesão Celular/imunologia; Sequência de Aminoácidos; Anticorpos Monoclonais/química; Anticorpos Monoclonais/genética; Linhagem Celular; Reações Cruzadas; Células Hep G2; Humanos; Região Variável de Imunoglobulina/química; Região Variável de Imunoglobulina/genética; Região Variável de Imunoglobulina/imunologia; Imunoprecipitação

Palavras-chave

Autoimmune disease; CADM1; Cross-reactive antibody; Germline repertoire; α-Actinin-4

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Actinina / Molécula 1 de Adesão Celular / Anticorpos Monoclonais Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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