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Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
Waage, Johannes; Standl, Marie; Curtin, John A; Jessen, Leon E; Thorsen, Jonathan; Tian, Chao; Schoettler, Nathan; Flores, Carlos; Abdellaoui, Abdel; Ahluwalia, Tarunveer S; Alves, Alexessander C; Amaral, Andre F S; Antó, Josep M; Arnold, Andreas; Barreto-Luis, Amalia; Baurecht, Hansjörg; van Beijsterveldt, Catharina E M; Bleecker, Eugene R; Bonàs-Guarch, Sílvia; Boomsma, Dorret I; Brix, Susanne; Bunyavanich, Supinda; Burchard, Esteban G; Chen, Zhanghua; Curjuric, Ivan; Custovic, Adnan; den Dekker, Herman T; Dharmage, Shyamali C; Dmitrieva, Julia; Duijts, Liesbeth; Ege, Markus J; Gauderman, W James; Georges, Michel; Gieger, Christian; Gilliland, Frank; Granell, Raquel; Gui, Hongsheng; Hansen, Torben; Heinrich, Joachim; Henderson, John; Hernandez-Pacheco, Natalia; Holt, Patrick; Imboden, Medea; Jaddoe, Vincent W V; Jarvelin, Marjo-Riitta; Jarvis, Deborah L; Jensen, Kamilla K; Jónsdóttir, Ingileif; Kabesch, Michael; Kaprio, Jaakko.
Afiliação
  • Waage J; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Standl M; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
  • Curtin JA; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester, UK.
  • Jessen LE; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Thorsen J; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Tian C; 23andMe, Inc., Mountain View, CA, USA.
  • Schoettler N; Department of Human Genetics, University of Chicago, Chicago, IL, USA.
  • Flores C; Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Tenerife, Spain.
  • Abdellaoui A; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
  • Ahluwalia TS; Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.
  • Alves AC; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Amaral AFS; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Antó JM; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.
  • Arnold A; Population Health and Occupational Disease, National Heart and Lung Institute, Imperial College London, London, UK.
  • Barreto-Luis A; ISGlobal, Barcelona, Spain.
  • Baurecht H; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
  • van Beijsterveldt CEM; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Bleecker ER; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
  • Bonàs-Guarch S; Clinic and Polyclinic of Dermatology, University Medicine Greifswald, Greifswald, Germany.
  • Boomsma DI; Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Tenerife, Spain.
  • Brix S; Department of Dermatology, Venereology and Allergology, University-Hospital Schleswig-Hostein, Campus Kiel, Kiel, Germany.
  • Bunyavanich S; Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.
  • Burchard EG; Divisions of Pharmacogenomics and Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona College of Medicine, Tucson, AZ, USA.
  • Chen Z; Barcelona Supercomputing Center (BSC), Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona, Spain.
  • Curjuric I; Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.
  • Custovic A; APH Amsterdam Public Health, Amsterdam, The Netherlands.
  • den Dekker HT; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
  • Dharmage SC; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Dmitrieva J; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
  • Duijts L; Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.
  • Ege MJ; Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA.
  • Gauderman WJ; University of Basel, Basel, Switzerland.
  • Georges M; Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Gieger C; Department of Paediatrics, Imperial College London, London, UK.
  • Gilliland F; The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Granell R; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Gui H; Department of Pediatrics, Division of Respiratory Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Hansen T; Allergy and Lung Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
  • Heinrich J; Laboratory of Animal Genomics, Unit of Medical Genomics, GIGA Institute, University of Liège, Liège, Belgium.
  • Henderson J; The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Hernandez-Pacheco N; Department of Pediatrics, Division of Respiratory Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Holt P; Department of Pediatrics, Division of Neonatology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Imboden M; LMU Munich, Dr von Hauner Children's Hospital, Munich, and German Center for Lung Research (DZL), Munich, Germany.
  • Jaddoe VWV; Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA.
  • Jarvelin MR; Laboratory of Animal Genomics, Unit of Medical Genomics, GIGA Institute, University of Liège, Liège, Belgium.
  • Jarvis DL; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
  • Jensen KK; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
  • Jónsdóttir I; Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA.
  • Kabesch M; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Kaprio J; Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, MI, USA.
Nat Genet ; 50(8): 1072-1080, 2018 08.
Article em En | MEDLINE | ID: mdl-30013184
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Genoma Humano / Predisposição Genética para Doença / Loci Gênicos / Rinite Alérgica / Antígenos HLA Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Genoma Humano / Predisposição Genética para Doença / Loci Gênicos / Rinite Alérgica / Antígenos HLA Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Dinamarca