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Heterogeneity of EGFR-mutant clones and PD-L1 highly expressing clones affects treatment efficacy of EGFR-TKI and PD-1 inhibitor.
Kunimasa, K; Nakamura, H; Sakai, K; Kimura, M; Inoue, T; Tamiya, M; Nishino, K; Kumagai, T; Nakatsuka, S; Endo, H; Inoue, M; Nishio, K; Imamura, F.
Afiliação
  • Kunimasa K; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan. Electronic address: kunimasa-ke@mc.pref.osaka.jp.
  • Nakamura H; Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka City, Japan.
  • Sakai K; Department of Genome Biology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
  • Kimura M; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan.
  • Inoue T; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan.
  • Tamiya M; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan.
  • Nishino K; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan.
  • Kumagai T; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan.
  • Nakatsuka S; Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka City, Japan.
  • Endo H; Department of Biochemistry, Osaka International Cancer Institute, Osaka City, Japan.
  • Inoue M; Department of Biochemistry, Osaka International Cancer Institute, Osaka City, Japan; Department of Clinical Bio-resource Research and Development, Graduate School of Medicine Kyoto University, Kyoto, Japan.
  • Nishio K; Department of Genome Biology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
  • Imamura F; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan.
Ann Oncol ; 29(10): 2145-2147, 2018 10 01.
Article em En | MEDLINE | ID: mdl-30099497
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 / Antineoplásicos Imunológicos / Mutação Limite: Female / Humans / Middle aged Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 / Antineoplásicos Imunológicos / Mutação Limite: Female / Humans / Middle aged Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article