Combination of IAP Antagonists and TNF-&#945;-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression.

Beug, Shawn T; Pichette, Stephanie J; St-Jean, Martine; Holbrook, Janelle; Walker, Danielle E; LaCasse, Eric C; Korneluk, Robert G

Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression.

Beug, Shawn T; Pichette, Stephanie J; St-Jean, Martine; Holbrook, Janelle; Walker, Danielle E; LaCasse, Eric C; Korneluk, Robert G.

Afiliação

Beug ST; Apoptosis Research Center, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Pichette SJ; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada.
St-Jean M; Apoptosis Research Center, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Holbrook J; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, ON, Canada.
Walker DE; Apoptosis Research Center, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
LaCasse EC; Apoptosis Research Center, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Korneluk RG; Apoptosis Research Center, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.

Mol Ther Oncolytics ; 10: 28-39, 2018 Sep 28.

Article em En | MEDLINE | ID: mdl-30101187

Palavras-chave

SMC; Smac mimetic compound; Smac mimetics; TNF-α; VSV; cIAP1/cIAP2; cancer; cellular inhibitor of apoptosis 1/2; immunotherapy; oncolytic virus; tumor necrosis factor alpha; vascular collapse; vesicular stomatitis virus

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Mol Ther Oncolytics Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá