Discriminative ability and clinical utility of the Timed Up and Go (TUG) in identifying falls risk in people with multiple sclerosis: a prospective cohort study.
Clin Rehabil
; 33(2): 317-326, 2019 Feb.
Article
em En
| MEDLINE
| ID: mdl-30103642
ABSTRACT
OBJECTIVE:
To investigate discriminative ability and clinical utility of the Timed Up and Go under single- and dual-task conditions between fallers and non-fallers in multiple sclerosis (MS).DESIGN:
Prospective cohort study.SETTING:
Neurology service in a tertiary hospital.SUBJECTS:
Participants were 101 people with MS and Expanded Disability Status Scale score of 3-6.5. One participant withdrew after the baseline assessment, and hence the data were analysed for 100 participants.INTERVENTIONS:
No specific intervention. MAINMEASURES:
Timed Up and Go and Timed Up and Go-Cognitive. Three-month prospective diaries recorded falls.RESULTS:
Mean age was 52.6 (SD 10.7) and 66 were female. Majority of the participants had progressive MS (72) and 73 used a walking aid; 56 participants recorded 791 falls. The area under the receiver operating characteristic curve values for Timed Up and Go and Timed Up and Go-Cognitive in distinguishing fallers (person with ⩾1 fall) from non-fallers are 0.60 and 0.57, respectively, and in distinguishing multiple fallers (⩾2 falls) the values are 0.46 and 0.43. A Timed Up and Go score of ⩾9 seconds has a sensitivity of 0.82 and a specificity of 0.34 to identify fallers and a sensitivity of 0.79 and a specificity of 0.27 to identify multiple fallers. A Timed Up and Go-Cognitive score of ⩾11 seconds has a sensitivity of 0.77 and a specificity of 0.30 to identify fallers and a sensitivity of 0.71 and a specificity of 0.26 to identify multiple fallers.CONCLUSION:
The Timed Up and Go and Timed Up and Go-Cognitive do not demonstrate sufficient clinical utility or discriminative ability for assessing falls risk in MS.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Acidentes por Quedas
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Cognição
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Atividade Motora
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Esclerose Múltipla
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Rehabil
Assunto da revista:
REABILITACAO
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Irlanda