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Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor.
Lindemann, Marcel; Hinz, Sonja; Deuther-Conrad, Winnie; Namasivayam, Vigneshwaran; Dukic-Stefanovic, Sladjana; Teodoro, Rodrigo; Toussaint, Magali; Kranz, Mathias; Juhl, Cathleen; Steinbach, Jörg; Brust, Peter; Müller, Christa E; Wenzel, Barbara.
Afiliação
  • Lindemann M; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
  • Hinz S; Pharma Center Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Deuther-Conrad W; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
  • Namasivayam V; Pharma Center Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Dukic-Stefanovic S; ROTOP Pharmaka GmbH, Dresden, Germany.
  • Teodoro R; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
  • Toussaint M; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
  • Kranz M; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
  • Juhl C; ROTOP Pharmaka GmbH, Dresden, Germany.
  • Steinbach J; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
  • Brust P; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
  • Müller CE; Pharma Center Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Wenzel B; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Leipzig, Germany. Electronic address: b.wenzel@hzdr.de.
Bioorg Med Chem ; 26(16): 4650-4663, 2018 09 01.
Article em En | MEDLINE | ID: mdl-30104122
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirazinas / Meios de Contraste / Compostos Radiofarmacêuticos / Receptor A2B de Adenosina / Tomografia por Emissão de Pósitrons Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirazinas / Meios de Contraste / Compostos Radiofarmacêuticos / Receptor A2B de Adenosina / Tomografia por Emissão de Pósitrons Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha