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Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
Zdralevic, Masa; Brand, Almut; Di Ianni, Lorenza; Dettmer, Katja; Reinders, Jörg; Singer, Katrin; Peter, Katrin; Schnell, Annette; Bruss, Christina; Decking, Sonja-Maria; Koehl, Gudrun; Felipe-Abrio, Blanca; Durivault, Jérôme; Bayer, Pascale; Evangelista, Marie; O'Brien, Thomas; Oefner, Peter J; Renner, Kathrin; Pouysségur, Jacques; Kreutz, Marina.
Afiliação
  • Zdralevic M; From the Université Côte d'Azur, IRCAN, CNRS, INSERM, Centre A. Lacassagne, 06189 Nice, France.
  • Brand A; From the Université Côte d'Azur, IRCAN, CNRS, INSERM, Centre A. Lacassagne, 06189 Nice, France.
  • Di Ianni L; the Departments of Internal Medicine III and.
  • Dettmer K; From the Université Côte d'Azur, IRCAN, CNRS, INSERM, Centre A. Lacassagne, 06189 Nice, France.
  • Reinders J; the Institute of Functional Genomics and.
  • Singer K; the Institute of Functional Genomics and.
  • Peter K; the Departments of Internal Medicine III and.
  • Schnell A; the Departments of Internal Medicine III and.
  • Bruss C; Center for Interventional Immunology, University of Regensburg, 93053 Regensburg, Germany.
  • Decking SM; the Departments of Internal Medicine III and.
  • Koehl G; the Departments of Internal Medicine III and.
  • Felipe-Abrio B; the Departments of Internal Medicine III and.
  • Durivault J; Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.
  • Bayer P; From the Université Côte d'Azur, IRCAN, CNRS, INSERM, Centre A. Lacassagne, 06189 Nice, France.
  • Evangelista M; the Medical Biology Department, Centre Scientifique de Monaco, Monaco MC98000.
  • O'Brien T; the Université Côte d'Azur, University Hospital Pasteur, Clinical Chemistry Laboratory, 06001 Nice, France.
  • Oefner PJ; Discovery and Translational Oncology, Genentech, South San Francisco, California 94080, and.
  • Renner K; Discovery and Translational Oncology, Genentech, South San Francisco, California 94080, and.
  • Pouysségur J; the Institute of Functional Genomics and.
  • Kreutz M; the Departments of Internal Medicine III and.
J Biol Chem ; 293(41): 15947-15961, 2018 10 12.
Article em En | MEDLINE | ID: mdl-30158244

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: L-Lactato Desidrogenase Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: L-Lactato Desidrogenase Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França