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Development and validation of simple step protein precipitation UHPLC-MS/MS methods for quantitation of temozolomide in cancer patient plasma samples.
El Mubarak, Mohamed A; Stylos, Evgenios K; Chatziathanasiadou, Maria V; Danika, Charikleia; Alexiou, George A; Tsekeris, Periklis; Renziehausen, Alexander; Crook, Tim; Syed, Nelofer; Sivolapenko, Gregory B; Tzakos, Andreas G.
Afiliação
  • El Mubarak MA; Department of Pharmacy, Laboratory of Pharmacokinetics, University of Patras, Patras, Greece.
  • Stylos EK; Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, GR-45110, Ioannina, Greece; Biotechnology Laboratory, Department of Biological Applications and Technology, University of Ioannina, Ioannina, 45110, Greece.
  • Chatziathanasiadou MV; Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, GR-45110, Ioannina, Greece.
  • Danika C; Department of Pharmacy, Laboratory of Pharmacokinetics, University of Patras, Patras, Greece.
  • Alexiou GA; Department of Neurosurgery, University Hospital of Ioannina, Ioannina, Greece.
  • Tsekeris P; Department of Radiation Oncology, University Hospital of Ioannina, Ioannina, Greece.
  • Renziehausen A; John Fulcher Neuro-Oncology Laboratory, Imperial College London, Hammersmith Hospital, London, UK.
  • Crook T; St Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, Surrey, UK.
  • Syed N; John Fulcher Neuro-Oncology Laboratory, Imperial College London, Hammersmith Hospital, London, UK.
  • Sivolapenko GB; Department of Pharmacy, Laboratory of Pharmacokinetics, University of Patras, Patras, Greece. Electronic address: gsivolap@upatras.gr.
  • Tzakos AG; Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, GR-45110, Ioannina, Greece. Electronic address: agtzakos@gmail.com.
J Pharm Biomed Anal ; 162: 164-170, 2019 Jan 05.
Article em En | MEDLINE | ID: mdl-30243056
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Cromatografia Líquida de Alta Pressão / Monitoramento de Medicamentos / Antineoplásicos Alquilantes / Espectrometria de Massas em Tandem / Cromatografia de Fase Reversa / Temozolomida Tipo de estudo: Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Grécia
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Cromatografia Líquida de Alta Pressão / Monitoramento de Medicamentos / Antineoplásicos Alquilantes / Espectrometria de Massas em Tandem / Cromatografia de Fase Reversa / Temozolomida Tipo de estudo: Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Grécia