Psychosocial Health and Lifestyle Behaviors in Young Adults Receiving Renal Replacement Therapy Compared to the General Population: Findings From the SPEAK Study.
Am J Kidney Dis
; 73(2): 194-205, 2019 02.
Article
em En
| MEDLINE
| ID: mdl-30293669
ABSTRACT
RATIONALE & OBJECTIVE:
Patients in late adolescence and early adulthood receiving renal replacement therapy (RRT) face disruption to normal activities, which affects well-being. We aimed to define psychosocial and lifestyle outcomes for young adults on RRT compared to the general population. STUDYDESIGN:
We undertook a cross-sectional survey (the SPEAK [Surveying Patients Experiencing Young Adult Kidney Failure] Study) using validated measures and general population comparator data from the Health Survey for England and Avon Longitudinal Study of Parents and Children. Additional clinical information was obtained from the UK Renal Registry. SETTING &PARTICIPANTS:
16- to 30-year-olds receiving RRT.OUTCOMES:
Psychosocial health and lifestyle behaviors. ANALYTICALAPPROACH:
We compared outcomes between populations using age- and sex-adjusted regression models, weighted to account for response bias by sex, ethnicity, and socioeconomic status. Our findings were used to update recent meta-analyses.RESULTS:
We recruited 976 young adults and 64% responded to the survey 417 (71%) with kidney transplants and 173 (29%) on dialysis therapy. Compared to the general population, young adults on RRT were less likely to be in a relationship and have children and more likely to live in the family home, receive no income, and be unable to work due to health. They had poorer quality of life, worse well-being, and twice the likelihood of a psychological disturbance (OR, 2.7; 95% CI, 2.0-3.7; P<0.001). They reported less smoking, alcohol and drug abuse, and crime. In a meta-analysis, our study showed the greatest differences in quality of life compared to the general population.LIMITATIONS:
Cross-sectional study design, meaning that we could not track the impact of treatment changes on the outcomes.CONCLUSIONS:
This study involving a large cohort of young adult transplant recipients and dialysis patients provides evidence of worse psychosocial outcomes but more positive lifestyle behaviors in young adults on RRT compared to the age-matched general population.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Comportamentos Relacionados com a Saúde
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Nível de Saúde
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Diálise Renal
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Transplante de Rim
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Falência Renal Crônica
/
Estilo de Vida
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Am J Kidney Dis
Ano de publicação:
2019
Tipo de documento:
Article