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Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers.
Liang, Jennifer; Zhou, Wenchao; Sakre, Nneha; DeVecchio, Jennifer; Ferrandon, Sylvain; Ting, Angela H; Bao, Shideng; Bissett, Ian; Church, James; Kalady, Matthew F.
Afiliação
  • Liang J; Department of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Zhou W; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Sakre N; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • DeVecchio J; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Ferrandon S; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Ting AH; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Bao S; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Bissett I; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Church J; Department of Surgery, University of Auckland, Auckland, OH, New Zealand.
  • Kalady MF; Department of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
Br J Cancer ; 119(10): 1267-1277, 2018 11.
Article em En | MEDLINE | ID: mdl-30318507

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Genes Supressores de Tumor / Neoplasias do Colo / Metilação de DNA / MicroRNAs / Ubiquitina-Proteína Ligases / Epigênese Genética / Proteínas Adaptadoras de Transdução de Sinal Limite: Animals / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Genes Supressores de Tumor / Neoplasias do Colo / Metilação de DNA / MicroRNAs / Ubiquitina-Proteína Ligases / Epigênese Genética / Proteínas Adaptadoras de Transdução de Sinal Limite: Animals / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos