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DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
Lee, Donghyun D; Leão, Ricardo; Komosa, Martin; Gallo, Marco; Zhang, Cindy H; Lipman, Tatiana; Remke, Marc; Heidari, Abolfazl; Nunes, Nuno Miguel; Apolónio, Joana D; Price, Aryeh J; De Mello, Ramon Andrade; Dias, João S; Huntsman, David; Hermanns, Thomas; Wild, Peter J; Vanner, Robert; Zadeh, Gelareh; Karamchandani, Jason; Das, Sunit; Taylor, Michael D; Hawkins, Cynthia E; Wasserman, Jonathan D; Figueiredo, Arnaldo; Hamilton, Robert J; Minden, Mark D; Wani, Khalida; Diplas, Bill; Yan, Hai; Aldape, Kenneth; Akbari, Mohammad R; Danesh, Arnavaz; Pugh, Trevor J; Dirks, Peter B; Castelo-Branco, Pedro; Tabori, Uri.
Afiliação
  • Lee DD; Program in Genetics and Genome Biology, and.
  • Leão R; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Komosa M; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Gallo M; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Zhang CH; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • Lipman T; Program in Genetics and Genome Biology, and.
  • Remke M; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Heidari A; Departments of Physiology and Pharmacology, Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada.
  • Nunes NM; Program in Genetics and Genome Biology, and.
  • Apolónio JD; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Price AJ; Program in Genetics and Genome Biology, and.
  • De Mello RA; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Dias JS; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, University Hospital Düsseldorf, Düsseldorf, Germany.
  • Huntsman D; Program in Genetics and Genome Biology, and.
  • Hermanns T; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Wild PJ; Program in Genetics and Genome Biology, and.
  • Vanner R; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Zadeh G; Department of Biomedical Sciences and Medicine, and.
  • Karamchandani J; Centro Hospitalar Universitário do Algarve, Faro, Portugal.
  • Das S; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Taylor MD; Department of Biomedical Sciences and Medicine, and.
  • Hawkins CE; Centro Hospitalar Universitário do Algarve, Faro, Portugal.
  • Wasserman JD; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Figueiredo A; Department of Urology, University Hospital Zürich, and.
  • Hamilton RJ; Institute of Pathology and Molecular Pathology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
  • Minden MD; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Wani K; Division of Neurosurgery, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.
  • Diplas B; Department of Pathology, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
  • Yan H; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Aldape K; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Akbari MR; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Danesh A; Division of Endocrinology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Pugh TJ; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • Dirks PB; Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
  • Castelo-Branco P; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Tabori U; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
J Clin Invest ; 129(1): 223-229, 2019 01 02.
Article em En | MEDLINE | ID: mdl-30358567

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Regulação Neoplásica da Expressão Gênica / Regiões Promotoras Genéticas / Telomerase / Metilação de DNA / Proteínas de Neoplasias Limite: Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Regulação Neoplásica da Expressão Gênica / Regiões Promotoras Genéticas / Telomerase / Metilação de DNA / Proteínas de Neoplasias Limite: Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2019 Tipo de documento: Article