Base-Controlled Three Component Reactions of Amines, Elemental Sulfur, and Styrenes: Synthesis of Thioamides under Metal-Free Conditions.

Zhang, Pingshun; Chen, Wanzhi; Liu, Miaochang; Wu, Huayue

Zhang, Pingshun; Chen, Wanzhi; Liu, Miaochang; Wu, Huayue.

Afiliação

Zhang P; Department of Chemistry , Zhejiang University , Yuquan Campus, Hangzhou 310007 , China.
Chen W; Department of Chemistry , Zhejiang University , Yuquan Campus, Hangzhou 310007 , China.
Liu M; College of Chemistry and Materials Engineering , Wenzhou University , Wenzhou 325027 , China.
Wu H; College of Chemistry and Materials Engineering , Wenzhou University , Wenzhou 325027 , China.

J Org Chem ; 83(23): 14269-14276, 2018 Dec 07.

Article em En | MEDLINE | ID: mdl-30394744

ABSTRACT

ABSTRACT

Three component reactions of olefins, amines, and sulfur were studied. Thioamidation of styrenes is base-controlled, and 2-phenylethanethioamides and benzothioamides were obtained selectively in the presence of two different bases. This protocol offers a simple and efficient procedure for the synthesis of thioamides.

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: J Org Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China