Heterologous Boost Following <i>Mycobacterium bovis BCG</i> Reduces the Late Persistent, Rather Than the Early Stage of Intranasal Tuberculosis Challenge Infection.

Wu, Yaqi; Cai, Ming; Ma, Jilei; Teng, Xindong; Tian, Maopeng; Bassuoney, Eman Borham Mohamed Borham; Fan, Xionglin

Heterologous Boost Following Mycobacterium bovis BCG Reduces the Late Persistent, Rather Than the Early Stage of Intranasal Tuberculosis Challenge Infection.

Wu, Yaqi; Cai, Ming; Ma, Jilei; Teng, Xindong; Tian, Maopeng; Bassuoney, Eman Borham Mohamed Borham; Fan, Xionglin.

Afiliação

Wu Y; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Cai M; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ma J; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Teng X; Shandong International Travel Healthcare Center, Shandong Entry-Exit Inspection and Quarantine Bureau, Qingdao, China.
Tian M; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bassuoney EBMB; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Fan X; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Front Immunol ; 9: 2439, 2018.

Article em En | MEDLINE | ID: mdl-30425711

Assuntos

Vacina BCG/imunologia; Tuberculose Latente/prevenção & controle; Mycobacterium bovis/imunologia; Tuberculose Pulmonar/imunologia; Vacinas de DNA/imunologia; Vacinas Sintéticas/imunologia; Adenoviridae/imunologia; Administração Intranasal; Animais; Antígenos de Bactérias/genética; Antígenos de Bactérias/imunologia; Linhagem Celular; Feminino; Células HEK293; Humanos; Imunização Secundária/métodos; Interferon gama/imunologia; Interleucina-2/imunologia; Tuberculose Latente/imunologia; Pulmão/citologia; Pulmão/imunologia; Camundongos; Camundongos Endogâmicos C57BL; Mycobacterium tuberculosis/imunologia; Células Th1/imunologia; Tuberculose Pulmonar/prevenção & controle

Palavras-chave

BCG; early stage of tuberculosis; heterologous boost; late persistent tuberculosis; memory T cells

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Vacina BCG / Vacinas Sintéticas / Vacinas de DNA / Tuberculose Latente / Mycobacterium bovis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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