Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.

Davis, Stephanie M; Collier, Lisa A; Goodwin, Sarah; Lukins, Douglas E; Powell, David K; Pennypacker, Keith R

Davis, Stephanie M; Collier, Lisa A; Goodwin, Sarah; Lukins, Douglas E; Powell, David K; Pennypacker, Keith R.

Afiliação

Davis SM; Department of Neurology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536, United States. Electronic address: stephanie.davis@uky.edu.
Collier LA; Department of Neurology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536, United States. Electronic address: lisa.collier1@uky.edu.
Goodwin S; Department of Neurology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536, United States. Electronic address: sarah.goodwin2@uky.edu.
Lukins DE; Department of Radiology, University of Kentucky, 800 Rose St., Lexington, KY 40536, United States. Electronic address: douglas.lukins@uky.edu.
Powell DK; Spinal Cord and Brain Injury Research Center, 741 S. Limestone, Lexington, KY 40536, United States. Electronic address: david.k.powell@uky.edu.
Pennypacker KR; Department of Neurology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536, United States; Department of Neuroscience, University of Kentucky, 800 Rose St., Lexington, KY 40536, United States. Electronic address: keith.pennypacker@uky.edu.

Brain Res ; 1707: 62-73, 2019 03 15.

Article em En | MEDLINE | ID: mdl-30445025

Assuntos

Fator Inibidor de Leucemia/farmacologia; Receptores de OSM-LIF/metabolismo; Acidente Vascular Cerebral/tratamento farmacológico; Fatores Etários; Animais; Encéfalo/metabolismo; Citocinas/metabolismo; Feminino; Interleucina-6/metabolismo; Fator Inibidor de Leucemia/metabolismo; Masculino; Neurônios/metabolismo; Neuroproteção; Ratos; Ratos Sprague-Dawley; Receptores de Citocinas/metabolismo; Fatores Sexuais; Acidente Vascular Cerebral/metabolismo; Resultado do Tratamento

Palavras-chave

Aging; Cytokine; Ischemia; Neuroprotection; Stroke

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / Fator Inibidor de Leucemia / Receptores de OSM-LIF Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Brain Res Ano de publicação: 2019 Tipo de documento: Article

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