OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans.

Kwon, Eun Young; Chung, Jae-Yong; Park, Hyo Jin; Kim, Bo Min; Kim, Minsuk; Choi, Ji Ha

Kwon, Eun Young; Chung, Jae-Yong; Park, Hyo Jin; Kim, Bo Min; Kim, Minsuk; Choi, Ji Ha.

Afiliação

Kwon EY; Department of Pharmacology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Korea.
Chung JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Bundang Hospital, Seoul, Korea.
Park HJ; Department of Pharmacology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Korea.
Kim BM; Department of Pharmacology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Korea.
Kim M; Department of Pharmacology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Korea.
Choi JH; Department of Pharmacology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Korea. jihachoi@ewha.ac.kr.

Sci Rep ; 8(1): 16965, 2018 11 16.

Article em En | MEDLINE | ID: mdl-30446679

Assuntos

Haplótipos; Metformina/farmacocinética; Proteínas de Transporte de Cátions Orgânicos/genética; Polimorfismo de Nucleotídeo Único; Regiões Promotoras Genéticas/genética; Adulto; Alelos; Área Sob a Curva; Feminino; Frequência do Gene; Humanos; Hipoglicemiantes/farmacocinética; Masculino; República da Coreia; Adulto Jovem

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Haplótipos / Regiões Promotoras Genéticas / Polimorfismo de Nucleotídeo Único / Proteínas de Transporte de Cátions Orgânicos / Metformina Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google