Canine Liver Fibrosis Model to Assess the Functions of Infused Autologous Bone Marrow-Derived Cells.
Methods Mol Biol
; 1905: 201-209, 2019.
Article
em En
| MEDLINE
| ID: mdl-30536102
ABSTRACT
Liver cirrhosis is the end stage of chronic liver disease, and the only radical treatment for decompensated liver cirrhosis is still liver transplantation. Development of effective regenerative therapy for liver cirrhosis is an urgent task. Before human clinical trials can be considered, the safety and efficacy of any planned protocol must be confirmed in medium-to-large animals. Therefore, we have developed a novel canine liver fibrosis model for proof of concept (POC) studies.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Células da Medula Óssea
/
Tetracloreto de Carbono
/
Transplante de Medula Óssea
/
Cirrose Hepática
Tipo de estudo:
Guideline
Limite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Methods Mol Biol
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Japão