EphA3 Downregulation by Hypermethylation Associated with Lymph Node Metastasis and TNM Stage in Colorectal Cancer.

Wang, Yong; Xuan, Zhuoqi; Wang, Baocheng; Zhang, Dongsheng; Zhang, Chuan; Wang, Jiandong; Sun, Yueming

Wang, Yong; Xuan, Zhuoqi; Wang, Baocheng; Zhang, Dongsheng; Zhang, Chuan; Wang, Jiandong; Sun, Yueming.

Afiliação

Wang Y; Department of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Xuan Z; Department of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Wang B; Department of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Zhang D; Department of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Zhang C; Department of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Wang J; Department of Pathology, Jinling Hospital, Nanjing University School of Medicine, No. 305, Zhong Shan Dong Lu, Nanjing, 210002, China. jd_wang@outlook.com.
Sun Y; Department of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China. jssym@vip.sina.com.

Dig Dis Sci ; 64(6): 1514-1522, 2019 06.

Article em En | MEDLINE | ID: mdl-30560328

Assuntos

Neoplasias Colorretais/genética; Metilação de DNA; Receptores Proteína Tirosina Quinases/genética; Neoplasias Colorretais/metabolismo; Neoplasias Colorretais/patologia; Ilhas de CpG; Regulação para Baixo; Feminino; Regulação Neoplásica da Expressão Gênica; Células HCT116; Células HT29; Humanos; Metástase Linfática; Masculino; Pessoa de Meia-Idade; Estadiamento de Neoplasias; Regiões Promotoras Genéticas; Receptores Proteína Tirosina Quinases/metabolismo; Receptor EphA3

Palavras-chave

CRC; EphA3; Metastasis; Methylation; TNM stage

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Receptores Proteína Tirosina Quinases / Metilação de DNA Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Dig Dis Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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