Lung transplantation in two cystic fibrosis patients infected with previously pandrug-resistant Burkholderia cepacia complex treated with ceftazidime-avibactam.
Infection
; 47(2): 289-292, 2019 Apr.
Article
em En
| MEDLINE
| ID: mdl-30565008
ABSTRACT
We describe two cystic fibrosis patients infected with pandrug-resistant Burkholderia cepacia complex, with the exception of ceftazidime-avibactam, who received prophylaxis with this antibiotic during lung transplantation. Although both patients had a post-operative relapse of respiratory infection, one with positive blood cultures, ceftazidime-avibactam treatment yielded a favourable outcome. 12 months after transplantation, one patient presented an excellent clinical outcome. However, the other patient died 10 months later due to severe B. cepacia sinusitis with intracranial invasion.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Ceftazidima
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Transplante de Pulmão
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Farmacorresistência Bacteriana Múltipla
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Complexo Burkholderia cepacia
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Compostos Azabicíclicos
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Antibacterianos
Tipo de estudo:
Etiology_studies
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Infection
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Espanha