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DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression.
Mäki-Nevala, Satu; Valo, Satu; Ristimäki, Ari; Sarhadi, Virinder; Knuutila, Sakari; Nyström, Minna; Renkonen-Sinisalo, Laura; Lepistö, Anna; Mecklin, Jukka-Pekka; Peltomäki, Päivi.
Afiliação
  • Mäki-Nevala S; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland. Electronic address: satu.maki-nevala@helsinki.fi.
  • Valo S; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.
  • Ristimäki A; Department of Pathology, HUSLAB, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Genome-Scale Biology Research Program, Research Programs Unit, University of Helsinki, Finland.
  • Sarhadi V; Department of Pathology, HUSLAB, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Knuutila S; Department of Pathology, HUSLAB, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Nyström M; Department of Biosciences, University of Helsinki, Helsinki, Finland.
  • Renkonen-Sinisalo L; Department of Surgery, Helsinki University Hospital, Helsinki, Finland.
  • Lepistö A; Department of Surgery, Helsinki University Hospital, Helsinki, Finland.
  • Mecklin JP; Sport and Health Sciences, University of Jyväskylä and Jyväskylä Central Hospital, Jyväskylä, Finland.
  • Peltomäki P; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.
EBioMedicine ; 39: 280-291, 2019 Jan.
Article em En | MEDLINE | ID: mdl-30578081
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Regiões Promotoras Genéticas / Metilação de DNA / Mutação Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: EBioMedicine Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Regiões Promotoras Genéticas / Metilação de DNA / Mutação Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: EBioMedicine Ano de publicação: 2019 Tipo de documento: Article