Characterization, antibacterial activity and antibiotic modifying action of the Caryocar coriaceum Wittm. pulp and almond fixed oil.
Nat Prod Res
; 34(22): 3239-3243, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-30663376
ABSTRACT
In this study the physicochemical characterization of the pulp and almond fixed oil was carried out; their antibacterial activity and aminoglycoside antibiotic modifying action against standard and multiresistant Gram-positive and -negative bacteria were investigated using the broth microdilution assay. Physical properties such as moisture, pH, acidity, peroxide index, relative density and refractive index indicate stability and chemical quality of the oils. In the GC/MS chemical composition analysis, a high unsaturated fatty acid content and the presence of oleic and palmitic acids were observed in the oils. In the antibacterial assay, more significant results were obtained for Escherichia coli, while other standard and multi-resistant strains presented MIC values ≥ 1024 µg/mL. Furthermore, the fixed oils in association with antibiotics were able to significantly improve antibacterial activity against S. aureus with a reduction in MICs.
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Bases de dados:
MEDLINE
Assunto principal:
Óleos de Plantas
/
Malpighiales
/
Antibacterianos
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Brasil