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Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung Cancer.
Liu, Pengfei; Xiang, Yuchen; Liu, Xuewen; Zhang, Te; Yang, Rui; Chen, Sen; Xu, Li; Yu, Qingqing; Zhao, Huzi; Zhang, Liang; Liu, Ying; Si, Yuan.
Afiliação
  • Liu P; Laboratory of Molecular Target Therapy of Cancer, Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, China. LiuPF_001@163.com.
  • Xiang Y; Laboratory of Molecular Target Therapy of Cancer, Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China. LiuPF_001@163.com.
  • Liu X; Laboratory of Molecular Target Therapy of Cancer, Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, China. xiangyc4026@163.com.
  • Zhang T; Laboratory of Molecular Target Therapy of Cancer, Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China. xiangyc4026@163.com.
  • Yang R; Laboratory of Molecular Target Therapy of Cancer, Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, China. liuxw1110@163.com.
  • Chen S; Laboratory of Molecular Target Therapy of Cancer, Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China. liuxw1110@163.com.
  • Xu L; Laboratory of Molecular Target Therapy of Cancer, Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China. zhangte519@163.com.
  • Yu Q; Laboratory of Molecular Target Therapy of Cancer, Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, China. yangr0512@163.com.
  • Zhao H; Laboratory of Molecular Target Therapy of Cancer, Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China. yangr0512@163.com.
  • Zhang L; Laboratory of Molecular Target Therapy of Cancer, Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, China. sener_chen@163.com.
  • Liu Y; Laboratory of Molecular Target Therapy of Cancer, Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China. sener_chen@163.com.
  • Si Y; Laboratory of Molecular Target Therapy of Cancer, Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China. xuli103028@sina.com.
Molecules ; 24(3)2019 Feb 12.
Article em En | MEDLINE | ID: mdl-30759826
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Triterpenos / Transdução de Sinais / Carcinoma Pulmonar de Células não Pequenas / Resistencia a Medicamentos Antineoplásicos / Gefitinibe / Neoplasias Pulmonares / Lisossomos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Triterpenos / Transdução de Sinais / Carcinoma Pulmonar de Células não Pequenas / Resistencia a Medicamentos Antineoplásicos / Gefitinibe / Neoplasias Pulmonares / Lisossomos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China