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Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key ß-Cell-Specific Disease Genes.
Fang, Zhou; Weng, Chen; Li, Haiyan; Tao, Ran; Mai, Weihua; Liu, Xiaoxiao; Lu, Leina; Lai, Sisi; Duan, Qing; Alvarez, Carlos; Arvan, Peter; Wynshaw-Boris, Anthony; Li, Yun; Pei, Yanxin; Jin, Fulai; Li, Yan.
Afiliação
  • Fang Z; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Weng C; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Li H; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Tao R; Center for Cancer and Immunology Research, Brain Tumor Institute, Children's National Medical Center, Washington, D.C. 20010, USA.
  • Mai W; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province 519000, China.
  • Liu X; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Lu L; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Lai S; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Duan Q; Department of Biostatistics, Department of Genetics, Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Alvarez C; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; The Biomedical Sciences Training Program (BSTP), School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Arvan P; Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.
  • Wynshaw-Boris A; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Li Y; Department of Biostatistics, Department of Genetics, Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Pei Y; Center for Cancer and Immunology Research, Brain Tumor Institute, Children's National Medical Center, Washington, D.C. 20010, USA.
  • Jin F; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; Department of Population and Quantitative Health Sciences, Department of Electrical Engineering and Computer Science, Case Comprehensive Cancer Center, Case Western Reserve Univ
  • Li Y; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address: yxl1379@case.edu.
Cell Rep ; 26(11): 3132-3144.e7, 2019 03 12.
Article em En | MEDLINE | ID: mdl-30865899
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Heterogeneidade Genética / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Transcriptoma Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Heterogeneidade Genética / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Transcriptoma Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos