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From single drug targets to synergistic network pharmacology in ischemic stroke.
Casas, Ana I; Hassan, Ahmed A; Larsen, Simon J; Gomez-Rangel, Vanessa; Elbatreek, Mahmoud; Kleikers, Pamela W M; Guney, Emre; Egea, Javier; López, Manuela G; Baumbach, Jan; Schmidt, Harald H H W.
Afiliação
  • Casas AI; Department of Pharmacology and Personalised Medicine, Maastricht Center for Systems Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6229 ER Maastricht, The Netherlands; a.casasguijarro@maastrichtuniversity.nl h.schmidt@maastrichtuniversity.nl.
  • Hassan AA; Department of Pharmacology and Personalised Medicine, Maastricht Center for Systems Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6229 ER Maastricht, The Netherlands.
  • Larsen SJ; Computational Biology Lab, Department of Mathematics and Computer Science, University of Southern Denmark, 5230 Odense, Denmark.
  • Gomez-Rangel V; Instituto Teofilo Hernando, Departamento de Farmacología, Facultad de Medicina, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
  • Elbatreek M; Department of Pharmacology and Personalised Medicine, Maastricht Center for Systems Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6229 ER Maastricht, The Netherlands.
  • Kleikers PWM; Department of Pharmacology and Personalised Medicine, Maastricht Center for Systems Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6229 ER Maastricht, The Netherlands.
  • Guney E; Department of Pharmacology and Personalised Medicine, Maastricht Center for Systems Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6229 ER Maastricht, The Netherlands.
  • Egea J; Research Programme on Biomedical Informatics, The Hospital del Mar Medical Research Institute and Pompeu Fabra University, 08003 Barcelona, Spain.
  • López MG; Servicio de Farmacología Clínica, Instituto de Investigación Sanitaria-Hospital Universitario de la Princesa, 28006 Madrid, Spain.
  • Baumbach J; Instituto Teofilo Hernando, Departamento de Farmacología, Facultad de Medicina, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
  • Schmidt HHHW; Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Munich, Germany.
Proc Natl Acad Sci U S A ; 116(14): 7129-7136, 2019 04 02.
Article em En | MEDLINE | ID: mdl-30894481

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Isquemia Encefálica / Óxido Nítrico Sintase / Acidente Vascular Cerebral / Descoberta de Drogas / NADPH Oxidase 4 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Isquemia Encefálica / Óxido Nítrico Sintase / Acidente Vascular Cerebral / Descoberta de Drogas / NADPH Oxidase 4 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article