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Successful Treatment of Severe Heparin-induced Thrombocytopenia with Intravenous Immunoglobulin, Platelet Transfusion and Rivaroxaban: A Case Report.
Huang, He; Lin, Ying; Yao, Rong-Xin; He, Mu-Qing; Lin, Xiao-Ji.
Afiliação
  • Huang H; Department of Hematology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Lin Y; Department of Hematology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Yao RX; Department of Hematology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • He MQ; Department of Hematology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Lin XJ; Department of Hematology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
Chin Med Sci J ; 34(1): 60-64, 2019 Mar 30.
Article em En | MEDLINE | ID: mdl-30961783
Heparin-induced thrombocytopenia (HIT) is a relatively infrequent complication of heparin administration. HIT can cause devastating thrombosis, making it one of the most serious adverse drug reactions encountered in clinical practice. We successfully treated a case of severe HIT presenting with thrombosis and life-threatening bleeding complications with intravenous immunoglobulin (IVIG), platelet transfusion and oral anticoagulant Rivaroxaban. In this case, we considered that IVIG played the most important role by preventing further thrombosis, increasing the platelet count, and ensuring the efficacy of Rivaroxaban. We therefore suggest that IVIG might be the optimal treatment for patients with this urgent condition.
Assuntos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Trombocitopenia / Heparina / Imunoglobulinas Intravenosas / Transfusão de Plaquetas / Rivaroxabana Limite: Aged80 / Female / Humans Idioma: En Revista: Chin Med Sci J Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Trombocitopenia / Heparina / Imunoglobulinas Intravenosas / Transfusão de Plaquetas / Rivaroxabana Limite: Aged80 / Female / Humans Idioma: En Revista: Chin Med Sci J Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China