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Epidemic threshold in pairwise models for clustered networks: closures and fast correlations.
Barnard, Rosanna C; Berthouze, Luc; Simon, Péter L; Kiss, István Z.
Afiliação
  • Barnard RC; Department of Mathematics, School of Mathematical and Physical Sciences, University of Sussex, Falmer, Brighton, BN1 9QH, UK.
  • Berthouze L; Centre for Computational Neuroscience and Robotics, University of Sussex, Falmer, Brighton, BN1 9QH, UK.
  • Simon PL; Institute of Mathematics, Eötvös Loránd University Budapest, Budapest, Hungary.
  • Kiss IZ; Numerical Analysis and Large Networks Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
J Math Biol ; 79(3): 823-860, 2019 08.
Article em En | MEDLINE | ID: mdl-31079178
The epidemic threshold is probably the most studied quantity in the modelling of epidemics on networks. For a large class of networks and dynamics, it is well studied and understood. However, it is less so for clustered networks where theoretical results are mostly limited to idealised networks. In this paper we focus on a class of models known as pairwise models where, to our knowledge, no analytical result for the epidemic threshold exists. We show that by exploiting the presence of fast variables and using some standard techniques from perturbation theory we are able to obtain the epidemic threshold analytically. We validate this new threshold by comparing it to the threshold based on the numerical solution of the full system. The agreement is found to be excellent over a wide range of values of the clustering coefficient, transmission rate and average degree of the network. Interestingly, we find that the analytical form of the threshold depends on the choice of closure, highlighting the importance of model selection when dealing with real-world epidemics. Nevertheless, we expect that our method will extend to other systems in which fast variables are present.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Simulação por Computador / Doenças Transmissíveis / Epidemias / Modelos Teóricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Math Biol Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Simulação por Computador / Doenças Transmissíveis / Epidemias / Modelos Teóricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Math Biol Ano de publicação: 2019 Tipo de documento: Article