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Novel multi-targeted inhibitors suppress ocular neovascularization by regulating unique gene sets.
Yin, Xiangke; Lin, Xianchai; Ren, Xiangrong; Yu, Bo; Liu, Lixian; Ye, Zhimin; Chen, Qishan; Lee, Chunsik; Lu, Weisi; Yu, Dechao; Li, Xuri.
Afiliação
  • Yin X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China.
  • Lin X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China.
  • Ren X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China.
  • Yu B; Larix Bioscience LLC, 1230 Bordeaux Drive, Sunnyvale, CA, 94089, USA.
  • Liu L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China.
  • Ye Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China.
  • Chen Q; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China.
  • Lee C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China.
  • Lu W; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China. Electronic address: luweisi3@mail.sysu.edu.cn.
  • Yu D; Innovent Biologics, Inc., 168 Dongping Street, Suzhou Industrial Park, 215123, PR China. Electronic address: michael.yu@innoventbio.com.
  • Li X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, PR China. Electronic address: lixr6@mail.sysu.edu.cn.
Pharmacol Res ; 146: 104277, 2019 08.
Article em En | MEDLINE | ID: mdl-31112749
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Receptor beta de Fator de Crescimento Derivado de Plaquetas / Inibidores da Angiogênese / Receptor 1 de Fatores de Crescimento do Endotélio Vascular / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Olho / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Receptor beta de Fator de Crescimento Derivado de Plaquetas / Inibidores da Angiogênese / Receptor 1 de Fatores de Crescimento do Endotélio Vascular / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Olho / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article