Molecular mechanism underlying anti-inflammatory activities of lirioresinol B dimethyl ether through suppression of NF-&#954;B and MAPK signaling in in vitro and in vivo models.

Su, Yunshu; Xiong, Sizheng; Lan, Hongwen; Xu, Lijun; Wei, Xiang

Molecular mechanism underlying anti-inflammatory activities of lirioresinol B dimethyl ether through suppression of NF-κB and MAPK signaling in in vitro and in vivo models.

Su, Yunshu; Xiong, Sizheng; Lan, Hongwen; Xu, Lijun; Wei, Xiang.

Afiliação

Su Y; Department of Cardiothorasic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China. Electronic address: micxu@163.com.
Xiong S; Department of Cardiothorasic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
Lan H; Department of Cardiothorasic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
Xu L; Department of Cardiothorasic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China. Electronic address: n803ve@163.com.
Wei X; Department of Cardiothorasic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China. Electronic address: xiangwei201808@163.com.

Int Immunopharmacol ; 73: 321-332, 2019 Aug.

Article em En | MEDLINE | ID: mdl-31129419

Assuntos

Anti-Inflamatórios/farmacologia; Furanos/farmacologia; Proteínas Quinases Ativadas por Mitógeno/metabolismo; NF-kappa B/metabolismo; Animais; Anti-Inflamatórios/uso terapêutico; Carragenina; Sobrevivência Celular/efeitos dos fármacos; Citocinas/metabolismo; Dinoprostona/metabolismo; Edema/induzido quimicamente; Edema/tratamento farmacológico; Adjuvante de Freund; Furanos/uso terapêutico; Hiperalgesia/induzido quimicamente; Hiperalgesia/tratamento farmacológico; Lipopolissacarídeos/farmacologia; Masculino; Camundongos; Óxido Nítrico/metabolismo; Proteínas Serina-Treonina Quinases/metabolismo; Células RAW 264.7; Transdução de Sinais/efeitos dos fármacos; Quinase Induzida por NF-kappaB

Palavras-chave

Anti-inflammatory; Carrageenan; Lirioresinol B dimethyl ether; MAPKs/AP-1; NF-κB

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: NF-kappa B / Proteínas Quinases Ativadas por Mitógeno / Furanos / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article

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