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Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene.
Franich, Nicholas R; Hickey, Miriam A; Zhu, Chunni; Osborne, Georgina F; Ali, Nadira; Chu, Tiffany; Bove, Nicholas H; Lemesre, Vincent; Lerner, Renata P; Zeitlin, Scott O; Howland, David; Neueder, Andreas; Landles, Christian; Bates, Gillian P; Chesselet, Marie-Francoise.
Afiliação
  • Franich NR; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
  • Hickey MA; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
  • Zhu C; Department of Pharmacology, University of Tartu, Tartu, Estonia.
  • Osborne GF; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
  • Ali N; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.
  • Chu T; UK Dementia Research Institute at UCL, University College London, London, UK.
  • Bove NH; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.
  • Lemesre V; UK Dementia Research Institute at UCL, University College London, London, UK.
  • Lerner RP; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
  • Zeitlin SO; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
  • Howland D; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
  • Neueder A; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
  • Landles C; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, Virginia.
  • Bates GP; CHDI Management/CHDI Foundation Inc., New York, New York.
  • Chesselet MF; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.
J Neurosci Res ; 97(12): 1590-1605, 2019 12.
Article em En | MEDLINE | ID: mdl-31282030
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Comportamento Animal / Doença de Huntington / Modelos Animais de Doenças / Proteína Huntingtina Limite: Animals Idioma: En Revista: J Neurosci Res Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Comportamento Animal / Doença de Huntington / Modelos Animais de Doenças / Proteína Huntingtina Limite: Animals Idioma: En Revista: J Neurosci Res Ano de publicação: 2019 Tipo de documento: Article