Effective glucose metabolism maintains low intracellular glucose in airway epithelial cells after exposure to hyperglycemia.

Bearham, Jade; Garnett, James P; Schroeder, Victoria; Biggart, Matthew G S; Baines, Deborah L

Bearham, Jade; Garnett, James P; Schroeder, Victoria; Biggart, Matthew G S; Baines, Deborah L.

Afiliação

Bearham J; Institute for Infection and Immunity, St. George's University of London, London, United Kingdom.
Garnett JP; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Schroeder V; Immunology and Respiratory Diseases Research, Boehringer Ingelheim Pharma and Company, Biberach an der Riss, Germany.
Biggart MGS; Immunology and Respiratory Diseases Research, Boehringer Ingelheim Pharma and Company, Biberach an der Riss, Germany.
Baines DL; Institute for Infection and Immunity, St. George's University of London, London, United Kingdom.

Am J Physiol Cell Physiol ; 317(5): C983-C992, 2019 11 01.

Article em En | MEDLINE | ID: mdl-31433692

Assuntos

Glucose/metabolismo; Hexoquinase/metabolismo; Hiperglicemia/metabolismo; Mucosa Respiratória/metabolismo; Células Cultivadas; Relação Dose-Resposta a Droga; Inibidores Enzimáticos/farmacologia; Hexoquinase/antagonistas & inibidores; Humanos; Piruvatos/farmacologia; Mucosa Respiratória/efeitos dos fármacos

Palavras-chave

airway; epithelial cell; glucose; hexokinase; metabolism

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Mucosa Respiratória / Glucose / Hexoquinase / Hiperglicemia Limite: Humans Idioma: En Revista: Am J Physiol Cell Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido

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