Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease.

Matsuda, Yusaku; Nonaka, Yosuke; Futakawa, Satoshi; Imai, Hirotaka; Akita, Kazumasa; Nishihata, Toshiaki; Fujiwara, Masatoshi; Ali, Yusuf; Bhisitkul, Robert B; Nakamura, Yoshikazu

Matsuda, Yusaku; Nonaka, Yosuke; Futakawa, Satoshi; Imai, Hirotaka; Akita, Kazumasa; Nishihata, Toshiaki; Fujiwara, Masatoshi; Ali, Yusuf; Bhisitkul, Robert B; Nakamura, Yoshikazu.

Afiliação

Matsuda Y; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Nonaka Y; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Futakawa S; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Imai H; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Akita K; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Nishihata T; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Fujiwara M; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Ali Y; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Bhisitkul RB; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA.
Nakamura Y; RIBOMIC, Inc., 3-16-13 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan; Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan. Electronic address: nak@ims.u-tokyo.ac.jp.

Mol Ther Nucleic Acids ; 17: 819-828, 2019 Sep 06.

Article em En | MEDLINE | ID: mdl-31454678

Palavras-chave

AMD; FGF2; VEGF inhibitors; angiogenesis; aptamer; fibrosis

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Texto completo: 1 Bases de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Mol Ther Nucleic Acids Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão

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