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A Phase 1 study of BAL101553, a novel tumor checkpoint controller targeting microtubules, administered as 48-h infusion in adult patients with advanced solid tumors.
Joerger, Markus; Stathis, Anastasios; Metaxas, Yannis; Hess, Dagmar; Mantiero, Mara; Mark, Michael; Volden, Matthias; Kaindl, Thomas; Engelhardt, Marc; Larger, Patrice; Lane, Heidi; Hafner, Peter; Levy, Nicole; Stuedeli, Silvia; Sessa, Cristiana; von Moos, Roger.
Afiliação
  • Joerger M; Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
  • Stathis A; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
  • Metaxas Y; Department of Medical Oncology, Cantonal Hospital Graubünden, Chur, Switzerland.
  • Hess D; Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
  • Mantiero M; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
  • Mark M; Department of Medical Oncology, Cantonal Hospital Graubünden, Chur, Switzerland.
  • Volden M; Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
  • Kaindl T; Basilea Pharmaceutica International Ltd, Grenzacherstrasse 487, PO Box, CH-4005, Basel, Switzerland. Thomas.Kaindl@basilea.com.
  • Engelhardt M; Basilea Pharmaceutica International Ltd, Grenzacherstrasse 487, PO Box, CH-4005, Basel, Switzerland.
  • Larger P; Basilea Pharmaceutica International Ltd, Grenzacherstrasse 487, PO Box, CH-4005, Basel, Switzerland.
  • Lane H; Basilea Pharmaceutica International Ltd, Grenzacherstrasse 487, PO Box, CH-4005, Basel, Switzerland.
  • Hafner P; Basilea Pharmaceutica International Ltd, Grenzacherstrasse 487, PO Box, CH-4005, Basel, Switzerland.
  • Levy N; Swiss Group for Clinical Cancer Research, Bern, Switzerland.
  • Stuedeli S; Swiss Group for Clinical Cancer Research, Bern, Switzerland.
  • Sessa C; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
  • von Moos R; Department of Medical Oncology, Cantonal Hospital Graubünden, Chur, Switzerland.
Invest New Drugs ; 38(4): 1067-1076, 2020 08.
Article em En | MEDLINE | ID: mdl-31471863

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Oxidiazóis / Benzimidazóis / Pró-Fármacos / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Oxidiazóis / Benzimidazóis / Pró-Fármacos / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça