Long-Term Carriage of Medicopsis romeroi, an Agent of Black-Grain Mycetoma, Presenting as Phaeohyphomycosis in a Renal Transplant Patient.
Mycopathologia
; 184(5): 671-676, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-31502092
ABSTRACT
Medicopsis species are rare fungal pathogens that frequently resist common antifungal therapies and are difficult to identify morphologically as conidia are produced in pycnidia, a key feature of coelomycetes. Immunocompromised patients are at risk of these infections, even after remote exposure, and typically present with phaeohyphomycoses without dissemination. We present the case of a renal transplant recipient 6.5 years post-transplant who developed a slowly progressive soft tissue infection mimicking a synovial cyst. A cultured isolate was identified as Medicopsis romeroi by sequencing of multiple ribosomal loci. The patient responded well to debridement and posaconazole therapy. Solid-organ transplant patients are at risk of opportunistic fungal infection long after transplant, and molecular methods are often required for definitive identification.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Ascomicetos
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Portador Sadio
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Hospedeiro Imunocomprometido
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Feoifomicose
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Transplantados
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
Limite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Mycopathologia
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos