Optimization of biocompatibility in a laser surface treated Mg-AZ31B alloy.
Mater Sci Eng C Mater Biol Appl
; 105: 110028, 2019 Dec.
Article
em En
| MEDLINE
| ID: mdl-31546463
Biodegradable bone implants can remove the need for subsequent bone-implant surgeries by controlled biomineralization and degradation. Although Mg-alloys generally possess biocompatible properties, they corrode rapidly, thereby preventing sufficient hydroxyapatite formation and biomineral growth. In an attempt to address these limitations, laser surface treatments were performed via the employment of a continuous wave Nd:YAG laser on the Mg-AZ31B alloy using laser fluences in the range of 1.06-4.24â¯J/mm2 (250-1000â¯W). The laser-treated samples were investigated for their wettability in simulated body fluid. In vitro analyses were performed in simulated body fluid to examine corrosion and biomineralization behavior on the laser-treated samples. Statistical optimization algorithms based on wettability data predicted an optimal laser fluence of 3.286J/mm2 (775â¯W) within the range of laser fluences used in the present study for achieving a balance between biodegradation and biomineralization. Confirmatory tests on optimized samples indicated an up to 84% grain size reduction in laser-treated surface regions, a several-fold increase in Mg17Al12 (ß) phase volume fraction, a reasonably abundant formation of hydroxyapatite, and increased rates of biomineralization that exceeded degradation. These findings indicate the potential of laser surface engineering to realize Mg-AZ31B alloy as a viable biodegradable bone implant material.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Materiais Biocompatíveis
/
Teste de Materiais
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Ligas
/
Lasers
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Magnésio
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Mater Sci Eng C Mater Biol Appl
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos