Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aß<sub>1-42</sub>-Injected Rats.

Jiang, Xia; Chen, Lin-Lin; Lan, Zhou; Xiong, Fan; Xu, Xiang; Yin, Yang-Yang; Li, Ping; Wang, Ping

Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aß_1-42-Injected Rats.

Jiang, Xia; Chen, Lin-Lin; Lan, Zhou; Xiong, Fan; Xu, Xiang; Yin, Yang-Yang; Li, Ping; Wang, Ping.

Afiliação

Jiang X; Department of Pathology, Hubei University of Chinese Medicine, Wuhan, 430065, People's Republic of China. jane_j_09@126.com.
Chen LL; New products of TCM senile Diseases Co-innovation Center of Hubei, Wuhan, 430065, People's Republic of China. jane_j_09@126.com.
Lan Z; New products of TCM senile Diseases Co-innovation Center of Hubei, Wuhan, 430065, People's Republic of China.
Xiong F; New products of TCM senile Diseases Co-innovation Center of Hubei, Wuhan, 430065, People's Republic of China.
Xu X; Department of Pathology, Hubei University of Chinese Medicine, Wuhan, 430065, People's Republic of China.
Yin YY; Department of Pathology, Hubei University of Chinese Medicine, Wuhan, 430065, People's Republic of China.
Li P; Department of Pathology, Hubei University of Chinese Medicine, Wuhan, 430065, People's Republic of China.
Wang P; Department of Pathology, Hubei University of Chinese Medicine, Wuhan, 430065, People's Republic of China.

Neurochem Res ; 44(12): 2708-2722, 2019 Dec.

Article em En | MEDLINE | ID: mdl-31612304

Assuntos

Doença de Alzheimer/tratamento farmacológico; Flavonoides/uso terapêutico; Homeostase/efeitos dos fármacos; Macroautofagia/efeitos dos fármacos; Fármacos Neuroprotetores/uso terapêutico; Doença de Alzheimer/induzido quimicamente; Peptídeos beta-Amiloides/administração & dosagem; Animais; Hipocampo/metabolismo; Hipocampo/patologia; Humanos; Injeções; Lisossomos/efeitos dos fármacos; Masculino; Aprendizagem em Labirinto/efeitos dos fármacos; Fragmentos de Peptídeos/administração & dosagem; Ratos Sprague-Dawley; Memória Espacial/efeitos dos fármacos

Palavras-chave

Alzheimer's disease; Autophagy; Aß; Memory deficit; Protein aggregation

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Flavonoides / Fármacos Neuroprotetores / Doença de Alzheimer / Macroautofagia / Homeostase Limite: Animals / Humans / Male Idioma: En Revista: Neurochem Res Ano de publicação: 2019 Tipo de documento: Article

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