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Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Luginina, Aleksandra; Gusach, Anastasiia; Marin, Egor; Mishin, Alexey; Brouillette, Rebecca; Popov, Petr; Shiriaeva, Anna; Besserer-Offroy, Élie; Longpré, Jean-Michel; Lyapina, Elizaveta; Ishchenko, Andrii; Patel, Nilkanth; Polovinkin, Vitaly; Safronova, Nadezhda; Bogorodskiy, Andrey; Edelweiss, Evelina; Hu, Hao; Weierstall, Uwe; Liu, Wei; Batyuk, Alexander; Gordeliy, Valentin; Han, Gye Won; Sarret, Philippe; Katritch, Vsevolod; Borshchevskiy, Valentin; Cherezov, Vadim.
Afiliação
  • Luginina A; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Gusach A; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Marin E; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Mishin A; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Brouillette R; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Quebec J1H 5N4, Canada.
  • Popov P; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Shiriaeva A; Departments of Chemistry and Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Besserer-Offroy É; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Quebec J1H 5N4, Canada.
  • Longpré JM; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Quebec J1H 5N4, Canada.
  • Lyapina E; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Ishchenko A; Departments of Chemistry and Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Patel N; Departments of Chemistry and Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Polovinkin V; Institute of Complex Systems, ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.
  • Safronova N; Institut de Biologie Structurale J.-P. Ebel, Université Grenoble Alpes-CEA-CNRS, Grenoble 38000, France.
  • Bogorodskiy A; ELI Beamlines, Institute of Physics, Czech Academy of Sciences, 18221 Prague, Czech Republic.
  • Edelweiss E; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Hu H; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
  • Weierstall U; Institut de Biologie Structurale J.-P. Ebel, Université Grenoble Alpes-CEA-CNRS, Grenoble 38000, France.
  • Liu W; Department of Physics, Arizona State University, Tempe, AZ 85287, USA.
  • Batyuk A; Biodesign Center for Applied Structural Discovery, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
  • Gordeliy V; Department of Physics, Arizona State University, Tempe, AZ 85287, USA.
  • Han GW; Biodesign Center for Applied Structural Discovery, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
  • Sarret P; Biodesign Center for Applied Structural Discovery, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
  • Katritch V; School of Molecular Sciences, Arizona State University, Tempe, AZ 85287, USA.
  • Borshchevskiy V; Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.
  • Cherezov V; Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Sci Adv ; 5(10): eaax2518, 2019 10.
Article em En | MEDLINE | ID: mdl-31633023
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Receptores de Leucotrienos / Antiasmáticos Limite: Humans Idioma: En Revista: Sci Adv Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Federação Russa
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Receptores de Leucotrienos / Antiasmáticos Limite: Humans Idioma: En Revista: Sci Adv Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Federação Russa