Early repolarization pattern in an ethnically diverse population: Increased risk in Hispanics.
Pacing Clin Electrophysiol
; 43(1): 30-36, 2020 01.
Article
em En
| MEDLINE
| ID: mdl-31693197
ABSTRACT
BACKGROUND:
Early repolarization (ER) pattern on ECG is associated with an increased mortality in Caucasians. This study analyzed the association between ER pattern and all-cause mortality in a population of multiple ethnicities.METHODS:
A total of 20 000 individuals were randomly selected and their ECGs were analyzed for ER pattern using the 2015 consensus end-QRS notching or slurring with a J-point (Jp) ≥0.1 mV in contiguous inferior or lateral leads. Exclusion criteria were age <18, QRS duration of ≥120 ms, and acute myocardial infarction. Kaplan-Meier survival curves were used to assess crude survival, and multivariable logistic regression models were used to determine predictors of all-cause mortality.RESULTS:
A total of 17 901 patients with a mean age of 53 met inclusion criteria. Individuals were 62% female, 14% White, 37% Black, 40% Hispanic, and 9% other. Median follow-up time was 6.4 years. ER pattern was noted in 995 (5.6%) patients. Jp ≥2 mm was noted in 282 (1.6%) patients. In those with ER pattern and Jp ≥1 mm, there was no difference in mortality when compared to individuals without Jp elevation (odds ratio [OR] 0.962, 95% confidence of interval [CI] 0.819-1.131). Patients with Jp ≥2 mm had a significantly increased all-cause mortality (OR 1.333, 95% CI 1.009-1.742). This increased mortality was also significant in Hispanic patients with Jp ≥2 mm (OR 1.584, 95% CI 1.003-2.502).CONCLUSION:
ER pattern with Jp ≥2 mm is associated with increased mortality in a multiethnic population, apparently driven by an increased risk in Hispanics.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Arritmias Cardíacas
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Hispânico ou Latino
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Sistema de Condução Cardíaco
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Pacing Clin Electrophysiol
Ano de publicação:
2020
Tipo de documento:
Article