In vivo immunogenicity assessment and vaccine efficacy evaluation of a chimeric tandem repeat of epitopic region of OMP31 antigen fused to interleukin 2 (IL-2) against Brucella melitensis in BALB/c mice.

Nazifi, Narges; Tahmoorespur, Mojtaba; Sekhavati, Mohammad Hadi; Haghparast, Alireza; Behroozikhah, Ali Mohammad

Nazifi, Narges; Tahmoorespur, Mojtaba; Sekhavati, Mohammad Hadi; Haghparast, Alireza; Behroozikhah, Ali Mohammad.

Afiliação

Nazifi N; Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran.
Tahmoorespur M; Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran. Tahmoores@um.ac.ir.
Sekhavati MH; Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran. sekhavati@um.ac.ir.
Haghparast A; Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Behroozikhah AM; Department of Brucellosis, Razi Vaccine and Serum Research institute, agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.

BMC Vet Res ; 15(1): 402, 2019 Nov 08.

Article em En | MEDLINE | ID: mdl-31703683

Assuntos

Proteínas da Membrana Bacteriana Externa/imunologia; Vacina contra Brucelose/genética; Brucella melitensis/imunologia; Brucelose/prevenção & controle; Animais; Proteínas da Membrana Bacteriana Externa/genética; Vacina contra Brucelose/imunologia; Brucelose/imunologia; Feminino; Imunoglobulina G; Interleucina-2; Camundongos Endogâmicos BALB C; Baço/microbiologia; Vacinas Sintéticas/imunologia

Palavras-chave

Adjuvant; Antibodies; Brucella melitensis; Brucellosis; Cytokines; Experimental epitope; Immunization; OMP31; Recombinant protein

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas da Membrana Bacteriana Externa / Brucelose / Vacina contra Brucelose / Brucella melitensis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: BMC Vet Res Assunto da revista: MEDICINA VETERINARIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Irã

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