The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer.
Chem Soc Rev
; 49(4): 1041-1056, 2020 Feb 21.
Article
em En
| MEDLINE
| ID: mdl-31845688
ABSTRACT
Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Fármacos Fotossensibilizantes
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Indóis
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Neoplasias
Limite:
Animals
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Humans
Idioma:
En
Revista:
Chem Soc Rev
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China