Oncostatin M, A Profibrogenic Mediator Overexpressed in Non-Alcoholic Fatty Liver Disease, Stimulates Migration of Hepatic Myofibroblasts.

Foglia, Beatrice; Sutti, Salvatore; Pedicini, Dario; Cannito, Stefania; Bocca, Claudia; Maggiora, Marina; Bevacqua, Maria Rosaria; Rosso, Chiara; Bugianesi, Elisabetta; Albano, Emanuele; Novo, Erica; Parola, Maurizio

Foglia, Beatrice; Sutti, Salvatore; Pedicini, Dario; Cannito, Stefania; Bocca, Claudia; Maggiora, Marina; Bevacqua, Maria Rosaria; Rosso, Chiara; Bugianesi, Elisabetta; Albano, Emanuele; Novo, Erica; Parola, Maurizio.

Afiliação

Foglia B; Department Clinical and Biological Science, Unit of Experimental Medicine and Clinical Pathology, University of Torino, 10125 Torino, Italy.
Sutti S; Department of Health Science, University of East Piedmont, 28100 Novara, Italy.
Pedicini D; IRCC, Istituto per la Ricerca e la Cura del Cancro, Candiolo, 10060 Torino, Italy.
Cannito S; Department Clinical and Biological Science, Unit of Experimental Medicine and Clinical Pathology, University of Torino, 10125 Torino, Italy.
Bocca C; Department Clinical and Biological Science, Unit of Experimental Medicine and Clinical Pathology, University of Torino, 10125 Torino, Italy.
Maggiora M; Department Clinical and Biological Science, Unit of Experimental Medicine and Clinical Pathology, University of Torino, 10125 Torino, Italy.
Bevacqua MR; Department Clinical and Biological Science, Unit of Experimental Medicine and Clinical Pathology, University of Torino, 10125 Torino, Italy.
Rosso C; Division of Gastroenterology and Hepatology, Department of Medical Science, University of Torino, 10154 Torino, Italy.
Bugianesi E; Division of Gastroenterology and Hepatology, Department of Medical Science, University of Torino, 10154 Torino, Italy.
Albano E; Department of Health Science, University of East Piedmont, 28100 Novara, Italy.
Novo E; Department Clinical and Biological Science, Unit of Experimental Medicine and Clinical Pathology, University of Torino, 10125 Torino, Italy.
Parola M; Department Clinical and Biological Science, Unit of Experimental Medicine and Clinical Pathology, University of Torino, 10125 Torino, Italy.

Cells ; 9(1)2019 12 20.

Article em En | MEDLINE | ID: mdl-31861914

Assuntos

Miofibroblastos/citologia; Hepatopatia Gordurosa não Alcoólica/genética; Subunidade beta de Receptor de Oncostatina M/genética; Oncostatina M/genética; Regulação para Cima; Animais; Linhagem Celular; Movimento Celular/efeitos dos fármacos; Modelos Animais de Doenças; Humanos; Fator 1 Induzível por Hipóxia/metabolismo; Camundongos; Miofibroblastos/metabolismo; Hepatopatia Gordurosa não Alcoólica/metabolismo; Oncostatina M/metabolismo; Subunidade beta de Receptor de Oncostatina M/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais; Fator A de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

NAFLD/NASH; Oncostatin M; VEGF-A; liver fibrosis; migration; myofibroblasts; reactive oxygen species

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Regulação para Cima / Oncostatina M / Subunidade beta de Receptor de Oncostatina M / Miofibroblastos / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cells Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália

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