Dynorphin and Enkephalin Opioid Peptides and Transcripts in Spinal Cord and Dorsal Root Ganglion During Peripheral Inflammatory Hyperalgesia and Allodynia.

Sapio, Matthew R; Iadarola, Michael J; Loydpierson, Amelia J; Kim, Jenny J; Thierry-Mieg, Danielle; Thierry-Mieg, Jean; Maric, Dragan; Mannes, Andrew J

Sapio, Matthew R; Iadarola, Michael J; Loydpierson, Amelia J; Kim, Jenny J; Thierry-Mieg, Danielle; Thierry-Mieg, Jean; Maric, Dragan; Mannes, Andrew J.

Afiliação

Sapio MR; Department of Perioperative Medicine, National Institutes of Health, Clinical Center, Bethesda, Maryland.
Iadarola MJ; Department of Perioperative Medicine, National Institutes of Health, Clinical Center, Bethesda, Maryland. Electronic address: michael.iadarola@nih.gov.
Loydpierson AJ; Department of Perioperative Medicine, National Institutes of Health, Clinical Center, Bethesda, Maryland.
Kim JJ; Department of Perioperative Medicine, National Institutes of Health, Clinical Center, Bethesda, Maryland.
Thierry-Mieg D; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.
Thierry-Mieg J; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.
Maric D; Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.
Mannes AJ; Department of Perioperative Medicine, National Institutes of Health, Clinical Center, Bethesda, Maryland.

J Pain ; 21(9-10): 988-1004, 2020.

Article em En | MEDLINE | ID: mdl-31931229

Assuntos

Dinorfinas/metabolismo; Encefalinas/metabolismo; Gânglios Espinais/metabolismo; Hiperalgesia/metabolismo; Mediadores da Inflamação/metabolismo; Medula Espinal/metabolismo; Animais; Dinorfinas/análise; Encefalinas/análise; Gânglios Espinais/química; Mediadores da Inflamação/análise; Masculino; Peptídeos Opioides/análise; Peptídeos Opioides/metabolismo; Fragmentos de Peptídeos/análise; Fragmentos de Peptídeos/metabolismo; RNA Mensageiro/análise; RNA Mensageiro/metabolismo; Ratos; Ratos Sprague-Dawley; Medula Espinal/química

Palavras-chave

Opioid; allodynia; chronic pain; gene expression; inflammation; morphine; neuropathic pain

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Medula Espinal / Dinorfinas / Encefalinas / Mediadores da Inflamação / Gânglios Espinais / Hiperalgesia Tipo de estudo: Prognostic_studies / Qualitative_research Limite: Animals Idioma: En Revista: J Pain Assunto da revista: NEUROLOGIA / PSICOFISIOLOGIA Ano de publicação: 2020 Tipo de documento: Article

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