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Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems.
Dijk, Frederike; Veenstra, Veronique L; Soer, Eline C; Dings, Mark P G; Zhao, Lan; Halfwerk, Johannes B; Hooijer, Gerrit K; Damhofer, Helene; Marzano, Marco; Steins, Anne; Waasdorp, Cynthia; Busch, Olivier R; Besselink, Marc G; Tol, Johanna A; Welling, Lieke; van Rijssen, Lennart B; Klompmaker, Sjors; Wilmink, Hanneke W; van Laarhoven, Hanneke W; Medema, Jan Paul; Vermeulen, Louis; van Hooff, Sander R; Koster, Jan; Verheij, Joanne; van de Vijver, Marc J; Wang, Xin; Bijlsma, Maarten F.
Afiliação
  • Dijk F; Department of Pathology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands. f.dijk@amsterdamumc.nl.
  • Veenstra VL; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Soer EC; Oncode Institute, Amsterdam, the Netherlands.
  • Dings MPG; Department of Pathology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Zhao L; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Halfwerk JB; Oncode Institute, Amsterdam, the Netherlands.
  • Hooijer GK; Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong.
  • Damhofer H; Department of Pathology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Marzano M; Department of Pathology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Steins A; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Waasdorp C; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, United States of America.
  • Busch OR; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Besselink MG; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Tol JA; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Welling L; Oncode Institute, Amsterdam, the Netherlands.
  • van Rijssen LB; Department of Surgery, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Klompmaker S; Department of Surgery, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Wilmink HW; Department of Surgery, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • van Laarhoven HW; Department of Surgery, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Medema JP; Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
  • Vermeulen L; Department of Surgery, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • van Hooff SR; Department of Surgery, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Koster J; Department of Medical Oncology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Verheij J; Department of Medical Oncology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • van de Vijver MJ; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Wang X; Oncode Institute, Amsterdam, the Netherlands.
  • Bijlsma MF; Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands.
Sci Rep ; 10(1): 337, 2020 01 15.
Article em En | MEDLINE | ID: mdl-31941932
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda