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c-Jun NH2 -Terminal Protein Kinase Phosphorylates the Nrf2-ECH Homology 6 Domain of Nuclear Factor Erythroid 2-Related Factor 2 and Downregulates Cytoprotective Genes in Acetaminophen-Induced Liver Injury in Mice.
Chen, Yiping; Liu, Kaihua; Zhang, Jingwen; Hai, Yan; Wang, Peng; Wang, Hongyan; Liu, Qiuyan; Wong, Catherine C L; Yao, Jun; Gao, Yang; Liao, Yijiao; Tang, Xiuwen; Wang, Xiu Jun.
Afiliação
  • Chen Y; Department of Pharmacology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Liu K; Department of Pharmacology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Zhang J; Department of Pharmacology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Hai Y; Department of Biochemistry and Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Wang P; Department of Pharmacology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Wang H; Department of Biochemistry and Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Liu Q; Department of Pharmacology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Wong CCL; Center for Precision Medicine Multi-Omics Research, Peking University Health Science Center, Beijing, China.
  • Yao J; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Gao Y; National Center for Protein Science (Shanghai), Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Liao Y; Department of Pharmacology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Tang X; Department of Biochemistry and Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
  • Wang XJ; Department of Biochemistry and Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, PR China.
Hepatology ; 71(5): 1787-1801, 2020 05.
Article em En | MEDLINE | ID: mdl-31945188
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Analgésicos não Narcóticos / Citoproteção / Proteína Quinase 8 Ativada por Mitógeno / Doença Hepática Induzida por Substâncias e Drogas / Fígado / Acetaminofen Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Hepatology Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Analgésicos não Narcóticos / Citoproteção / Proteína Quinase 8 Ativada por Mitógeno / Doença Hepática Induzida por Substâncias e Drogas / Fígado / Acetaminofen Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Hepatology Ano de publicação: 2020 Tipo de documento: Article